Aldosterone as a modifier of chemical composition of urine
Speaking about the impact of aldosterone on chemical composition of urine,
it should be pointed out that it plays a very important role since it affects
kidneys, which, in their turn, are responsible for the formation of urine. In
order to better understand the way aldosterone modifies the composition of urine,
it is firstly necessary to dwell upon the role of aldosterone.
Aldosterone is a steroid secreted by the cortex of the adrenal gland and its
main function is the regulation of the body’s electrolyte balance. As
it has been already said aldosterone affects directly kidneys by decreasing
the amount of sodium-ion excretion, with accompanying retention of water, and,
at the same time, increase the amount of potassium-ion excretion.
Consequently it is possible to speak about the change of the composition of
urine depending on the amount of aldosterone. In actuality it may be expressed,
for instance, in the increased amount of potassium in urine, while the amount
of sodium will be less significant. However, normally the amount of these components
is insignificant since water constitutes 95% of urine.
In such a situation a patalogically elevated aldosterone secretion with concomitant
excessive retention of salt and water often results in edema. At the same time
any changes in the composition urine, which may result from the aldosterone
secretion higher than normal, can indicate at some diseases of not only urogenital
organs but also of some disorders of other body systems.
Obviously a deep understanding of such impact of aldosterone on the composition
of urine and a human organism at large are particularly important for a nurse
because it provides the possibility to reveal and prevent possible health problems
on the early stages of development of certain diseases and act adequately.
The role of respiratory system in controlling acid-base balance
Respiratory system is vitally important for human organism as well as for many
other living beings. One of its functions is controlling acid-base balance,
providing normal functioning of all organs of a human body.
First of all it is probably necessary to briefly define acid-base balance in
order to better understand the role of respiratory system in its controlling.
In fact acid-base balance may be defined as the state that exists when acidic
and basic ions in solution neutralise each other.
Furthermore, it should be pointed out that metabolic reactions are very sensitive
to pH level of the fluid in which they occur. This is because hydronium ions
can influence enzyme function. At first glance it seems that it is basically
kidneys that are responsible for this and the kidneys maintain blood plasma
acid-base homeostasis by hydronium regulation. But it is also true that gain
and loss of hydromium should be balanced and respiratory system plays a very
important role in this process since the sources of hydrogen ion gain are carbon
dioxide, the amount of which is regulated by gas exchange that is impossible
without respiratory system. Also hyperventilation, i.e. abnormally fast or deep
respiration resulting in the loss of carbon dioxide from the blood, may cause
both gain and loss of hydrogen ions. In such a way, hyperventilation may result,
for instance, in elevated amount of carbon dioxide that leads to increasing
of the amount of hydrogen ions, or vice versa, if such changes are very significant
it may break the acid-base balance.
Obviously it is important to know in order to realise what may be the consequences
of hyperventilation for instance, or what may be the cause of the break of acid-base


